Mathematical Biology Seminar - Fall 2023
Seminars are typically held on Wednesdays at 1:00PM in-person in CULM 505 or online via Zoom unless otherwise noted. Please note the location listed in the schedule below.
For questions about the seminar schedule, please contact Kristina Wicke.
September 27Matthew Junge, Baruch College, CUNY Location: CULM 505 Chase-escape Stochastic models in which parasite expansion is restricted to the sites occupied by their hosts were introduced by ecologists in the 90s. Most big theoretical questions remain unanswered. I'll describe our efforts to understand these dynamics on lattices, trees, and the configuration model. |
October 4Daniele Avitabile, Vrije Universiteit Amsterdam Location: TBA Title: TBA Abstract: TBA |
October 11Celeste Vallejo, DILIsym/Simulations Plus Location: Zoom An Introduction to Mathematical Modeling in Drug Development Using GastroPlus and DILIsym Modeling and simulation provide support for drug development at all stages of the drug lifecycle. Machine learning models can help to select the lead drug candidate during the drug discovery phase. Physiologically based pharmacokinetic (PBPK) models can help to predict the first-in-human dose during the pre-clinical phase or the appropriate drug dose in special populations during the clinical trial phase. Quantitative systems pharmacology/toxicology (QSP/QST) models can help to predict drug efficacy/toxicity during either the pre-clinical or clinical trial phase. In this talk, I will give a brief introduction to drug development as well as the types of models that are used to solve the most pressing questions in the drug development space. An introduction to PBPK models will be given and the PBPK software, GastroPlus, will be used as illustration. An introduction to QSP/QST models will be given and the QST software, DILIsym, will be used as illustration. |
November 1Deren Eaton, Columbia University Location: CULM 505 Linking Phylogenetic Inference at Genome-wide and Local Genealogical Scales Abstract: TBA |
November 15John Nardini, The College of New Jersey Location: CULM 505 Title: TBA Abstract: TBA |
September 26, 2023